Tuesday, 31 May 2016

Supercooling
As we have noted, whole-body supercooling allows many insects and fish to survive the winter.
Surprisingly, this is also true for some mammals, including bats and a particularly adroit Alaskan ground squirrel.
that can cool without freezing to about -3 degrees C while it hibernates, despite nominal
blood freezing points (determined by freezing samples using an osmometer) above -0.6 degrees C .
Supercooling has recently formed the basis of a British company,
which preserves enzymes and even whole cells by cooling them in tiny droplets of water to temperatures several degrees below their freezing point

The Future Of Resurrection
and the prospect of immortality.


Modern biology has given us an idea of reviving or lost ones by  reducing their body's temperature to about -220 degree Celsius to
prevent  damage to the cells.Their blood is also drained out and replaced with liquid nitrogen to preserve their body's cells.
 This is known as Cryogenics or Cryobiology.





In physicscryogenics is the study of the production and behaviour of materials at very low temperature.
Cryobiology is the branch of biology that studies the effects of low temperatures on living things within Earth's cryosphere or in science.

Cryobiology history can be traced back to antiquity. As early as in 2500 BC, low temperatures were used in Egypt in medicine. The use of cold was recommended by Hippocrates to stop bleeding and swelling. With the emergence of modern science, Robert Boyle studied the effects of low temperatures on animals.

 Large organs such as hearts are usually stored and transported, for short times only, at cool but not freezing temperatures for transplantation in the ancient past, especially the period of classical and other human civilizations before the Middle Ages.


With the emergence of modern science, Robert Boyle studied the effects of low temperatures on animals.
Large organs such as hearts are usually stored and transported, for short times only, at cool but not freezing temperatures for transplantation
Controlled-rate and slow freezing are well established techniques pioneered in the early 1970's which enabled the first human embryo frozen birth (Zoe Leyland) in 1984.
The number of live births from 'slow frozen' embryos is some 300,000 to 400,000 or 20% of the estimated 3 million in vitro fertilized births. Dr Christopher Chen, Australia, reported the world’s first pregnancy using slow-frozen oocytes from a British controlled-rate freezer in 1986.

The Society for Cryobiology was founded in 1964 to bring together those from the biological, medical, and physical sciences who have a common interest in the effects of low temperatures on biological systems.
The purpose of the Society is to promote scientific research in low temperature biology, to improve scientific understanding in this field.
This international meeting offers opportunities for presentation and discussion of the most up-to-date research in cryobiology, as well as reviewing specific aspects through symposia and workshops.The Society for Low Temperature Biology was founded in 1964 and became a registered charity in 2003 with the purpose of promoting research into the effects of low temperatures on all types of organisms and their constituent cells, tissues, and organs.

Many people have been saved using the principle of cryobiology -- their body temperature had been reduced to prevent their cells from getting damaged.



For example:

A toddler who had fallen into an icy stream was dead almost for one and an half hour but now is alive and well because of the doctors who saved/resurrected him.

State police said the boy fell into a tributary of Buffalo Creek, outside Mifflinburg, about 6 pm. March 11, while playing with two of his brothers. A neighbour, found the boy unresponsive on a grassy knoll in the stream about a quarter of mile away. Emergency personnel immediately began CPR, which continued uninterrupted as they rushed to Evangelical Community Hospital near Lewisburg, then boarded and a helicopter for a trip to Geisinger (USA), where a team was waiting in the emergency room.

Doctors knew that when he was found, he had no pulse and no respiration. For one hour and 41 minutes, rescuers administered CPR in a desperate effort to revive him. When he was found, his body temperature was less than 77 Degrees Fahrenheit. The doctors started raising his body temperature to 90 Degree Fahrenheit and did not increase it any more to prevent damage to the brain.
Gardell's father, Doyle Martin, a truck driver,  had just returned from Chicago and arrived at the hospital a short time later. He called out his son's name and asked whether  he wanted to play truck and to his joy and surprise his son opened his eyes !!
It was remarkable that Gardell could be discharged just five days later. He had broken ribs due to the CPR effort and a slight tremor.
Gardell had no chance of surviving were it not for the CPR. His age and low body temperature also were factors that saved his life. Since his body temperature had gone down, doctors were able to save him because he had gone into a hypothermic (frozen) state. Hypothermia protects the organs, because their oxygen and metabolic needs are less when they are cool.
That's why those same rescuers are using words like "amazing" and "miracle" to describe young Gardell Martin's return home five days later. He is healthy and giggling and playing again with his siblings.    

The principles of cryobiology had been used to preserve his brain cells and reduce the metabolism rate of his body cells to save/resurrect him.

You could see these videos to get a better understanding :
Low temperature damage in cells can be divided into damage produced by three effects:
(i) low temperature
Homeotherms (warm blooded animals like us) may be seriously damaged if our core temperature falls even several degrees for a sustained period.
(ii) direct effects of freezing
Freezing, however, is often deadly. On the scale of organs, the formation of ice can cause mechanical damage by expansion, or rupture as pointed ice crystals grow through the tissue. Further, if the ice forms inside the cell, the cell almost always dies.
The price for the cryopreservation of the whole body is $200,000 and $80,000 for
head only.
Cryonics are the efforts to save lives so that persons beyond the modern medicines
can be preserved for decades until a proper future medicine technology can restore
the person to full health and to life. The word sounds like fiction but it is based on
modern science.
Cryonics are based on three facts that are known improperly:
  1. When the basic structure is properly preserved, life can be stopped and restored again:
The chemistry of human's life is stopped by preserving his embryo for years. They have
survived cooling to temperatures to stop the brain and the organs from fuctioning upto an
hour. From this, biology tells us that life is a particular structure of matter. If the cell
structure is preserved properly, life can be stopped and restarted.

 2. Preservation of biological structure by vitrification:

Cryoprotectants( high concentration of chemicals ) are added to cells to permits the tissue
to be cooled at very low temperatures with little or no formation of ice. Vitrification is the
state of no ice formations below temperatures of -120°C. It is now possible to physically vitrify organs as large as the human brain, achieving excellent structural preservation without freezing.

3. Methods for repairing structure at the molecular level can now be foreseen.   

The emerging science of nanotechnology will eventually lead to devices capable of extensive tissue repair  and regeneration, including repair of individual cells one molecule at a time. Any preserved
person at which the basic brain structures encoding memory and personality remain intact, the future
of nanomedicine could theoretically recover him.

Cryonics should work:

1 If the survival of structure means the survival of the person.
2 If the essential structure can be preserved sufficiently by cold.
3 If the injuries of the preservation process can be repaired by the forseeable technology.

How to prevent death?

Death mainly occurs when chemistry of life becomes so disorganized that the normal operation itself
cannot restore the body. A hundred years ago, cardiac arrest was irreversible. Everyone declared that
people whose heart stopped beating was dead. Death is believed to occur after 4 to 6 minutes after the heart stopped beating. It is because it is difficult to revive the brain after the heart stops beating. However, with a new modern medicinal technology, more than 10 minutes of cardiac arrest can be
survived now without brain injury.  Real death occurs when cell structure and chemistry become so disorganized that no technology could restore the original state. This is called the information-theoretic criterion for death. That is certainly the case for death pronounced on the basis of absent "vital signs" today. The object of cryonics is to prevent death by preserving sufficient cell structure and chemistry so that recovery (including recovery of memory and personality) remains possible by foreseeable technology